More About the Stem Cell Unit
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The NIH Stem Cell Unit (l-r): Kye-Yoon Park, Barbara Mallon, Rebecca Hamilton, and Kevin Chen.
To allow scientists to select which lines are most suitable for their intended experiments, the research community has consistently requested that available cell lines be more fully characterized.
To address this important need, the NIH Intramural Research Program has created the NIH Stem Cell Unit (SCU). The purpose of the Unit is to have a side-by-side comparison of the 21 hESC lines approved under prior presidential policy, which was revoked March 9, 2009, by President Barack Obama's Executive Order 13505. As per the July 7, 2009, NIH stem cell guidelines, the eligibility of the use of these lines in NIH-supported research will be determined at a later date.
The Unit's main goal is to identify—and share with the research community—the similarities and differences between the hESC lines when subjected to a standardized paradigm.
The assays performed by this Unit are overseen by a steering committee of leading stem cell biologists in both the extramural and NIH intramural research community. Pamela Gehron Robey, Ph.D. of NIDCR is the Acting Director and provides day-to-day direction.
- Kuznetsov SA, Cherman N, Robey PG. In vivo bone formation by progeny of human embryonic stem cells. Stem Cells and Development. 2010 Sep 14 [Epub ahead of print].
- Cimato T, Beers J, Ding S, Ma M, McCoy JP, Boehm M, Nabel EG. (2009) Neuropilin-1 identifies endothelial precursors in human and murine embryonic stem cells before CD34 expression. Circulation. 119(16):2170–8.
- Xing Yan, Haiyan Qin, Cunye Qu, Rocky S Tuan, Songtao Shi, George TJ Huang. (2009) iPS cells reprogrammed from mesenchymal-like stem/progenitor cells of dental tissue origin. Stem Cells and Development. 19(4):469–80.
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