National Human Neural Stem Cell Resource:
The National Human Neural Stem Cell Resource (NHNSCR www.nhnscr.org), is pleased to announce that they have created an induced pluripotent stem cell (iPSC) biorepository and now have available dozens of fibroblast and iPSC lines derived from patients with idiopathic autism as well as controls and patients with FMR1 gene mutations (both full- and pre-mutations as well as isogenic derivations). Neural stem cells that we have differentiated from these lines are also available. Moreover, full clinical information for each of the lines is available.
All of the cultures are established under an NIH grant (R01HD059967), entitled "An Open Repository of Autism iPSCs and their derivatives". This effort is in close collaboration with Dr. Randi Hagerman of the UCDavis MIND Institute.
In addition to acting as a biorepository for cell lines, the NHNSCR also acts as a training facility, bringing in scientists who wish to use these new cell lines in their research and giving them the essential skills to do so. Two recent publications detail the methods that our laboratory uses: Schwartz, PH, and Wesselschmidt, RW, eds., Methods in Molecular Biology, 767:1–461, 2011, Human Pluripotent Stem Cells—Methods and Protocols; and Stover, et al., Journal of Neuroscience Research, 91(10):1247–62, 2013, Process-Based Expansion and Neural Differentiation of Human Pluripotent Stem Cells for Transplantation and Disease-Modeling.
For more information, please e-mail Dr. Phil Schwartz at firstname.lastname@example.org or visit our web site at www.nhnscr.org.